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CNN —Scientists say they are closer to understanding the best way to make the human body receptive to an organ donation from another species, an effort that could help solve an ongoing shortage of organs. More than 100,000 people in the US are on the transplant waiting list, and an average of 17 die every day while waiting. Doctors have spent decades experimenting with alternatives, and many now see potential in replacing failing human organs with genetically modified pig organs. Xenotransplantation, as cross-species organ transplantation is called, is still in the early stages. There are no human clinical trials taking place that have been approved by the US Food and Drug Administration, but the researchers behind a study published Thursday in the Journal of Clinical Investigation say their findings might bring human trials even closer.
Persons: Jayme Locke, Locke, that’s, Sheri Krams, , Krams, Dr, Sanjay Gupta, Mandy Ford, Ford, ” Ford Organizations: CNN —, US Food and Drug Administration, Investigation, University of Alabama, Heersink, of Medicine, FDA, Transplantation, Heersink School of Medicine, Stanford Medicine, UAB, Parsons Model, CNN, CNN Health, Emory Transplant Center Locations: United States
CNN —New advancements in transplanting pig kidneys to humans, detailed by two separate research teams on Wednesday, mark key steps forward in the evolving field of xenotransplantation, the use of non-human tissues or organs to treat medical conditions in humans. Both research teams used genetically modified pig kidneys that were transplanted into recipients experiencing brain death in what is considered pre-clinical human research. Other studies have demonstrated that this can occur when pig kidneys are transplanted in non-human primates. The team has been monitoring pig kidney transplants in a brain-dead decedent – a man named Maurice Miller, known as Mo, who died of a brain tumor – for nearly two months. “Over the last 20 years, we’ve gained a lot of information about how pig kidneys work to replace the functions in primates.
Persons: , Jayme Locke, Locke, ” Locke, NYU Langone, Maurice Miller, Mo, Robert Montgomery, Dr, Sanjay Gupta, “ We’re, Adam Griesemer, we’ve, ’ –, we’re Organizations: CNN, University of Alabama, Birmingham Heersink School of Medicine, New York University, Health, Comprehensive Transplant Institute, , UAB, NYU, NYU Langone Transplant Institute, CNN Health, Liver Transplant, FDA, US Department of Health, Human, Transplantation Network
The 26-year-old had been recently removed from his parents' health insurance plan and was about $300 short of the $1,300 he needed to pay for his insulin medication, his mother said. Though drugmakers often offer programs that can lower the out-of-pocket cost of insulin for both insured and uninsured patients, the financial burden can still be devastating for some. Why insulin remains unaffordableBut why does insulin — a medication that’s been around for more than 100 years — remain unaffordable for many people in the U.S.? Meanwhile, state and federal lawmakers are pushing for legislation that would lower the out-of-pocket cost for patients on insulin. She is pushing for more states to adopt the Alec Smith Insulin Affordability Act, which provides an emergency 30-day supply of insulin to patients for $35.
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